Shengqing Wu
Masters
Co-advised with Krishna Mahadevan
Publications within the group (1)
Do protein representations encode variant function? Diagnosing residue-level protein attributions via embedding-space gradients / bioRxiv / '26
Introduces IGLOO, a diagnostic framework that evaluates whether residue-level embedding gradients from protein language models faithfully capture functional importance against synthetic and experimental fitness landscapes.
Rana A. Barghout, Shengqing Wu, William Chau, José Manuel Barraza-Chavez, Paola Driza, Radhakrishnan Mahadevan, Benjamin Sanchez-Lengeling